Overview
Selank is studied in research involving neuropeptide signaling, the GABAergic system, and neuroimmune interactions. Researchers investigate how synthetic analogs of the peptide tuftsin interact with signaling pathways in neural and immune tissue.
Technical Research Details
Selank is a synthetic heptapeptide analog of tuftsin, an endogenous tetrapeptide fragment of immunoglobulin G. It carries a C-terminal Pro-Gly-Pro extension intended to increase resistance to enzymatic degradation. Selank has been the subject of laboratory research involving GABAergic signaling, brain-derived neurotrophic factor (BDNF) expression, monoamine turnover, and the expression of immune-related genes in preclinical models.
This product is supplied exclusively as a research material. It is not intended for diagnostic, therapeutic, dietary, cosmetic, veterinary, or human use.
Research Notes
Selank is derived from tuftsin, a peptide associated in the research literature with modulation of immune cell activity. The synthetic analog adds a Pro-Gly-Pro sequence to the C-terminus, a modification frequently cited as slowing peptidase cleavage relative to the parent peptide.
Preclinical literature has examined Selank in the context of GABA-A receptor signaling, BDNF and neurotrophic gene expression, serotonergic and dopaminergic activity, and the expression of interleukin- and interferon-related genes. Behavioral research in rodent models has been used to characterize these signaling effects.
Because this research area is still developing relative to more extensively characterized peptides, researchers should treat mechanistic findings as an active and evolving area of study rather than settled conclusions.
Documentation
Supplier-provided laboratory documentation is available for this product. This report was not independently commissioned by Alpha Tides PNW — see our Certificates of Analysis page for the full document and source notes.
Storage Notes
Maintaining compound integrity requires proper storage before and after reconstitution:
- Before reconstitution: Store the lyophilized vial at -20°C, away from light and moisture. Bring to room temperature before opening to prevent condensation.
- After reconstitution: Refrigerate at 2–8°C and use within 28 days. Avoid repeated freeze-thaw cycles.
- Recommended solvent: Bacteriostatic water for most research protocols.
For complete handling procedures, see the Research Compound Storage Guide and Reconstitution Protocol.
Related Research
- How to Store Research Compounds Properly — Storage protocols for lyophilized research compounds
- How to Reconstitute Lyophilized Compounds — Step-by-step reconstitution guide
- Research Hub — Full library of compound guides and research references
Selank is intended strictly for laboratory research by qualified professionals. Not FDA approved. Not for human or animal use. By purchasing, the buyer confirms the product will be used solely for in vitro research in compliance with all applicable laws.
Laboratory Testing
Certificate available
